**OXIS INTERNATIONAL**
DATED:1-06-2010
VISIT (WWW.OXIS.COM) FOR MORE INFORMATION
http://www.oxis.com



This company is engaged in the research, development and sale of products that counteract the harmful effects of “oxidative stress.”The companyis the premiere provider for the potent antioxidant, Ergothioneine and through their patented synthetic manufacturing process remains the only significant commercial source of pure l-ergothioneine worldwide.


WHAT IS OXIDATIVE STRESS?
->Oxidative stress refers to the situations in which the body’s antioxidant and other defensive abilities to combat free radicals (a.k.a highly reactive species of oxygen and nitrogen) are overwhelmed and one’s normal healthy balance is either lost or severely compromised.

SOME USEFUL TERMS

1.ANTI AGING->>>>
Life extension, also known as antiaging medicine, experimental gerontology, and biomedical gerontology, refers to attempts to slow down or reverse the processes of aging to extend both the maximum and average lifespan. Some researchers in this area, and "life extensionists" or "longevists" (who wish to achieve longer lives for themselves), believe that future breakthroughs in tissue rejuvenation with stem cells, molecular repair, and organ replacement (such as with artificial organs or xenotransplantations) will eventually enable humans to have indefinite lifespans through complete rejuvenation to a youthful condition.

2.ANTIOXIDANTS->>>>
An antioxidant is a molecule capable of slowing or preventing the oxidation of other molecules. Oxidation is a chemical reaction that transfers electrons from a substance to an oxidizing agent. Oxidation reactions can produce free radicals, which start chain reactions that damage cells. Antioxidants terminate these chain reactions by removing free radical intermediates, and inhibit other oxidation reactions by being oxidized themselves. As a result, antioxidants are often reducing agents such as thiols, ascorbic acid or polyphenols.

3.GLUTATHIONE->>>>
Glutathione (GSH) is a tripeptide. It contains an unusual peptide linkage between the amine group of cysteine and the carboxyl group of the glutamate side chain. Glutathione, an antioxidant, helps protect cells from reactive oxygen species such as free radicals and peroxides.Glutathione is nucleophilic at sulfur and attacks poisonous electrophilic conjugate acceptors.

4.PENNY STOCK->>>>
In the United States, a penny stock is a common stock that trades for less than five dollars a share and is traded over the counter (OTC) through quotation services such as the OTC Bulletin Board or the Pink Sheets. Although penny stocks are said to be "thinly traded," share volumes traded daily can be in the hundreds of millions for a sub-penny stock. Legitimate information on penny stock companies can be difficult to find and a stock can be easily manipulated.

5.FREE RADICALS->>>>
The free-radical theory of aging (FRTA) states that organisms age because cells accumulate free radical damage over time. A free radical is any atom or molecule that has a single unpaired electron in an outer shell. While a few free radicals such as melanin are not chemically reactive, most biologically-relevant free radicals are highly reactive. For most biological structures, free radical damage is closely associated with oxidative damage. Antioxidants are reducing agents, and limit oxidative damage to biological structures by passivating free radicals.
Strictly speaking, the free radical theory is only concerned with free radicals such as superoxide ( O2- ), but it has since been expanded to encompass oxidative damage from reactive oxygen species such as H2O2, or OH-.



PRODUCT FOCUS

Company's products include

THERAPEUTIC NUTRACEUTICAL PRODUCTS, COSMECEUTICAL PRODUCTS AND PROPRIETARY FORMULATIONS and CLINICAL PRODUCTS

that are developed internally and/or out-licensed to biotech and pharmaceutical companies as drug candidates.
Company focus on naturally occurring protective substances since they are more likely to be both safe and efficacious.There primary products incorporate and emphasize the multifaceted “super antioxidant” compound, L-­Ergothioneine (“ERGO”), as a key component. We own several patents and pending applications related to ERGO that cover current and planned products relevant to our nutraceutical and cosmecuetical businesses. Our patents and patent applications address ERGO’s protective effects and activities and the ERGO manufacturing process.


OXIS’ CONSUMER PRODUCTS…BASED ON POWERFUL NATURAL SUBSTANCES
OXIS is developing and plans to sell Nutraceutical and Cosmecuetical products featuring natural ingredients believed to have beneficial effects on human health. OXIS’ first products will include L-Ergothioneine (ERGO) as a key component. ERGO is a very powerful, multifaceted antioxidant. The remarkable properties of ERGO are described in detail in the Ergothioneine section of this website. OXIS has patented the synthesis process for L-Ergothioneine and has outsourced product manufacturing to a company that can provide ERGO in commercial and GMP produced quantities to meet our product needs.
OXIS’ consumer products strategy addresses very important health concerns including aging and age-related disorders that are increasing with trends in US demographics. These concerns include:

•Brain health
•Immunity against diseases
•Anti-aging/skin health
•Inflammation
•Detoxification
•Blood sugar regulation